Here, we show that functionalization of the 4-arylidene position of the fluorescent curcumin scaffold with an aryl nitrogen mustard provides a stable Hck inhibitor (Kd = 50 ± 10 nM). The mustard curcumin derivative preferentially interacts with the inactive conformation of Hck, similar to type-II kinase inhibitors that are less promiscuous. Mor

(January 23, 2024, 1:55 pm) UPDATED AGAIN: The owner Abraham was nice enough to comp a replacement meal and it was absolutely executed as I originally expected. The halal chicken was deliciously cooked to perfection The Carolina Reaper sauce is truly what is supposed to be so if you're not a professional great seeker, this isn't for you! Меж�

(January 23, 2024, 1:55 pm) UPDATED AGAIN: The owner Abraham was nice enough to comp a replacement meal and it was absolutely executed as I originally expected. The halal chicken was deliciously cooked to perfection The Carolina Reaper sauce is truly what is supposed to be so if you're not a professional great seeker, this isn't for you! Общ�

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